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This Adverse Outcome Pathway (AOP) describes the linkage between oxidative DNA damage and irreversible genomic damage (chromosomal aberrations and mutations). DNA damage is considered an important contributor to the adverse health effects of many environmental toxicants and this AOP may thus be of widespread use to the regulatory community. Although increase in oxidative DNA damage is the molecular initiating event for this AOP, there are numerous upstream key events that can also lead to DNA oxidation. Thus, this AOP may be expanded upstream, and could be incorporated into a variety of AOP networks. Furthermore, the AOP points to critical research gaps required to establish the quantitative associations and modulating factors that connect KEs across the AOP, and highlights the utility of novel test methods in understanding and evaluating the implications of oxidative DNA damage. This AOP is referred to as AOP 296 in the Collaborative Adverse Outcome Pathway Wiki (AOP-Wiki).
In addition to private pension fund and life insurance assets, several countries have accumulated large amounts of pension assets in their national pension reserve funds. Pension reserve fund refers to assets set aside by otherwise pay-as-you-go systems in preparation for the rising fiscal costs resulting from the predicted ageing of the population over the next few decades.
Good infrastructure is crucial to a country’s development and continued success. Russia’s developmental goals require new and upgraded infrastructure throughout its territory. Private investment in capital projects will be vital for Russia to meet these goals. To facilitate private investment, the Russian government has embarked on a series of reforms aimed at improving the investment climate and creating a robust institutional framework for private sector participation in concessions and Public-Private Partnerships (PPPs). The OECD’s 2012 Council Recommendation on Principles for Public Governance of Public-Private Partnerships (the PPP Recommendation) aims to support governments facing trade-offs between three demands inherent in a PPP project process. This article provides an overview of the alignment of the policies of the Russian Federation in the area of public governance of PPPs with these recommendations.
JEL classification: H41, H54, H57
Keywords: Council recommendations, public private partnerships, Russian Federation, value for money
This paper presents a general overview of recent work on sustainable development indicators in OECD countries. It provides an overview of on-going work for developing “agreed” indicators that measure progress across the three dimensions of sustainable development (economic, social and environmental). The paper then takes a more specific look at the approaches to sustainable development indicators adopted by different countries and highlights the challenges of having one set of standard international indicators across the various countries ...
This paper is based on seven national reports on national policies concerned with entrepreneurialism in universities as the context for a more detailed study of entrepreneurial behaviour in universities in the seven countries. It claims that the entrepreneurial university is a useful generic epithet to describe the manifold changes in mission, management and funding that many universities in Europe have experienced in the past two decades. The concept of university entrepreneurialism in most countries is linked to the “third mission” that is supplementing the long established teaching and academic research functions of universities and other higher education institutions. However, some governments are also concerned to encourage universities to embody the teaching of entrepreneurialism in at least some of their conventional courses. Five main drivers of entrepreneurial activities in the countries taking part in the “European Universities for Entrepreneurship: their role in the Europe of Knowledge”, (EUEREK) study are identified: ideology; expansion in the number of institutions; the knowledge society; globalisation; financial stringency. In some countries, especially in Eastern Europe there has been rapid growth in numbers of private higher education institutions. There are questions about whether this is an indication of entrepreneurialism, or of lack of entrepreneurial dynamism in the established public universities .The paper concludes with a preliminary review of managerial and governance changes in universities and colleges accompanying the growth of entrepreneurial and third mission activities.
Modern risk management has become an important tool for achieving strategic debt targets in the OECD area. In essence, risk management policies, based on the use of formal methods, are now an integral part of debt management in most OECD jurisdictions. In general, risk management tolerances and policies are approved (and often set) by the Ministry of Finance (or other appropriate Ministry). This strategy about risks entails an explicit political decision about the trade-off between costs and risks. The actual risk management operation is often run at a separate agency responsible for management of the sovereign debt or at the central bank if it manages the debt, and is typically segregated from other treasury...
The IEA analysis, however, finds that contrary to these views, the NOCs actually operate with a high degree of independence from the Chinese government, and their investments have in fact largely boosted global supplies of oil and gas, which other importers rely on.
This paper reviews first the fiscal policy recommendations by the EU, the IMF and the OECD for Finland, Greece, Ireland, Luxembourg, the Netherlands, Portugal and Spain. All these countries had inflation above the euro area average in early 2001, some by a considerable margin. The fiscal policy prescriptions deviate little, the EU, the IMF and the OECD generally recommending an active use of fiscal policy. There are some exceptions, however. The next section examines indicators of excess demand in these countries. This is followed by a review of the factors that help or hinder market-based adjustment, including simulations to gauge their effect. Market-based adjustment to demand shocks depends critically on whether the effect of a lower real interest rate is strong relative to the loss in competitiveness, on the size of wealth effects, on wage and price setting behavior, on the supply response and on the strength of trade integration. Simulations suggest that market-based ...
There is a growing awareness of the need to transform food systems. Yet successful actions require sound evidence: on the extent, characteristics, and drivers of issues; on the effectiveness of different policy instruments, and their synergies and trade-offs; on how policy proposals would affect stakeholders; and on citizens’ values and preferences. There are considerable evidence gaps on many of these aspects. This paper presents the main findings from the OECD project “Overcoming Evidence Gaps on Food Systems,” which aimed to identify different types of evidence gaps, as well as pragmatic approaches to overcome these. The project explored this question through three “deep dives” on food insecurity and food assistance programmes across OECD countries, gender and food systems, and environmental impacts along food supply chains. Overall, there is a strong case for greater investment in overcoming evidence gaps for food systems.
Food systems are expected to provide food security and nutrition, to contribute to the livelihoods of millions, and to do so in an environmentally sustainable way. The broad outlines of these challenges are clear, and in many cases evidence exists on how better policies can improve the performance of food systems. But there are considerable gaps in data and evidence. This paper provides a panoramic overview of different types of evidence gaps on food systems and their causes, and makes the case that better evidence is needed to enable better policies. At the same time, evidence will never be complete. Policy makers and the research community thus need to adopt a pragmatic approach, focusing on where better evidence can make the biggest difference.
Considerable efforts have been devoted to understanding and developing technologies and practices that can help the agricultural sector reduce its greenhouse gas emissions and adapt to the impacts of climate change. The uptake of these "climate-friendly" technologies and practices, however, remains low. This report, based on a comprehensive review of the literature, analyses barriers that may prevent farmers from adopting climate-friendly practices. A multitude of potential barriers exist, some associated with farm-level constraints, others operating at the sector level, or created by existing policies. A series of recommendations are made to properly identify these types of barriers and to select the right instruments that would work to implement effective policy solutions.
This paper was prepared for the OECD-IEA Climate Change Expert Group (formerly called the Annex I Expert Group) for the purpose of providing useful and timely input on specific topics relevant to international negotiations under the United Nations Framework Convention on Climate Change (UNFCCC). The papers do not represent the views of the OECD, the IEA, or their member countries, rather they are Secretariat information papers intended to help inform countries as well as the UNFCCC audience on key technical issues in the international climate change negotiations.
Overcoming administrative fragmentation to build an integrated public transport network is one of the main actions taken in the Madrid Region to improve mobility. The lack of a regional development plan and the poor linkages between transport and urban development policies are, however, the main obstacles to fostering accessibility. The paper argues that a regional development plan and spatial planning to underpin transport investment decisions are needed to make the most of transport infrastructure and foster growth, well-being and effective environmental policies. This paper aims to reveal policy lessons from the experience of the Madrid Region in fostering urban mobility and accessibility, which could inspire policy change in other EU cities.