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Pharmacogenetics: Opportunities and Challenges for Health Innovation

image of Pharmacogenetics: Opportunities and Challenges for Health Innovation

Pharmacogenetics helps us understand the relationship between an individual’s genetic make-up and the way medicines work for each person. This book reviews the use of pharmacogenetics across all stages of the health innovation cycle from research through to uptake by doctors and patients. It focuses on how to optimise the use of pharmacogenetics to deliver effective innovations for public health, and design policies that enhance their economic and social benefits. The book argues for large-scale studies to validate the biomarkers that underpin pharmacogenetics and policies to share the cost and risk of using  pharmacogenetics to improve the use of existing  medicines. Governments and others need to align regulatory, reimbursement and other incentives and work  with industry to measure better the impacts of pharmacogenetics. Health systems need to take positive steps to adapt to the use of pharmacogenetics and ensure that health professionals receive adequate training.

English

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Physician and Patient Demand for Pharmacogenetics

This chapter reviews current evidence of physicians’ attitudes to pharmacogenetics. It also covers patients’ perspectives and possible ethical and equity issues, particularly those concerning developing countries. It closes with consideration of the opportunities and challenges for incorporating pharmacogenetics in clinical care as well as potential organisational and system-wide hurdles. This will necessarily create both technical and educational challenges for health professionals. Successful integration of pharmacogenetics will depend upon appropriate infrastructure and trained personnel.

English

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