Responsibilities for research integrity and security are distributed across multiple actors in the international research ecosystem. These include, national governments, research funding agencies, research institutions, universities, academic associations, and intergovernmental organisations. This report describes policy initiatives and actions to safeguard national and economic security whilst protecting freedom of enquiry, promoting international research cooperation, and ensuring openness and non-discrimination. It includes examples of actions that are being taking to prevent foreign interference, manage risks, and help ensure trust in science in the future, and offers recommendations to help countries develop effective policies to strengthen research security as part of a broader framework of research integrity.