In order for all to benefit from new jobs growth, interventions are required to overcome the multi-faceted barriers that some people confront to accessing employment. These barriers can be immediate (such as lack of childcare) and more entrenched (such as drugs and health problems). This chapter highlights cross-sector initiatives that have been put in place to tackle more entrenched issues, focusing on particular populations (such as recent immigrants) and particular places (such as areas of deprivation in cities). Employers are important partners, to make workplaces better adapted to people with particular needs, and to reduce discrimination. At a time of widespread government austerity, new sources of finance and new methods of service delivery may be needed to ensure that resource intensive and long-term support is still available to those that need it.