Establishing sound institutional arrangements for the delivery of gender equality policy, including clear roles and responsibilities and adequate capacity and resourcing, is key to tackling gender inequalities. The Czech Republic has taken some steps to strengthen its institutional architecture for gender equality in recent years, but further efforts could be envisaged to promote a co-ordinated approach across the government. This chapter first presents an overview of the whole-of-government institutional framework for gender equality and mainstreaming in the Czech Republic. It then analyses the roles, responsibilities, capacities and capabilities of the institutional actors tasked with promoting the country’s gender equality agenda at the national level and assesses challenges and scope for improvement. It concludes with a set of targeted policy recommendations to reinforce the existing institutional set-up, with the aim of supporting the Czech Republic in achieving its gender equality goals.