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Safety Assessment of Transgenic Organisms in the Environment, Volume 8

OECD Consensus Document of the Biology of Mosquito Aedes aegypti

image of Safety Assessment of Transgenic Organisms in the Environment, Volume 8

Volume 8 of the Series contains the first biosafety ‘consensus document’ to deal with the biology of an insect, the mosquito Aedes aegypti. Issued by the OECD Working Group on the Harmonisation of Regulatory Oversight in Biotechnology, the science-based consensus documents collate information for use during the regulatory risk assessment of biotechnology products, i.e. transgenic organisms (plants, animals, micro-organisms) when intended for release in the environment. Ae. aegypti mosquito is vectoring yellow fever, dengue, Zika and Chikungunya diseases in tropical and sub-tropical regions worldwide. Biotechnological applications are developed to control the mosquito population and reduce virus transmission. The book provides information on Ae. aegypti taxonomy, morphology, life cycle, reproductive biology, genetics, ecology, interactions with other species and the environment. The mosquito effects on human and animal health, and the control strategies/specific programmes to limit its development are also summarised.

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Human and animal health affected by mosquitoes

This annex deals with the pathogens and diseases transmitted by mosquitoes to humans and animals. The main arbovirus infections of humans in the diverse regions of the world are summarised. More details are given on the dengue virus including its four viral serotypes, the range of symptoms affecting humans, the past and current epidemics of dengue (mainly vectored by Aedes aegypti and other aedine species) including its increasing spread over the past fifteen years. Few elements are also provided on virus transmission to animals by Ae. aegypti, and on vertical transmission.

English

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