The changing natural and economic global environment offers the agri-food sector challenges and opportunities. Innovation leading to increased productivity and sustainability will be required to help the sector meet expectations in a context of higher and more variable prices, stronger demand and resource constraints. Agricultural Knowledge and Innovation Systems are diverse and evolving from a linear approach to a more collaborative approach between countries and members of the Agricultural Knowledge and Information System (AKIS): public and private sector, higher education, research centres, producers, extension services and institutions specialised in technology transfer. In this context, networking is gaining in importance. The INNOVAGRO network has been created to foster international collaboration and communication cross border and continent to help the agri-food sector meet emerging challenges and size opportunities.