Technological change is set to have profound impacts over the next 10-15 years, widely disrupting economies and societies. As the world faces multiple challenges, including ageing, climate change, and natural resource depletion, technology will be called upon to contribute new or better solutions to emerging problems. These socio-ecological demands will shape the future dynamics of technological change, as will developments in science and technology. This chapter discusses ten key or emerging technologies that are among the most promising and potentially most disruptive and that carry significant risks. The choice of technologies is based on the findings of a few major foresight exercises carried out in recent years. The ten technologies are as follows: the Internet of Things; big data analytics; artificial intelligence; neurotechnologies; nano/microsatellites; nanomaterials; additive manufacturing; advanced energy storage technologies; synthetic biology; and blockchain. The chapter describes each technology in turn, highlighting some of its possible socioeconomic impacts and exploring related policy issues. A final section highlights some common themes across the ten technologies.