This chapter looks into policies which aim to make institutions more favourable to business start-up and operation by groups that are disadvantaged or under-represented in entrepreneurship. Institutions include regulations that directly affect the costs of conducting business activities, as well as the values, standards and norms that indirectly influence entrepreneurship through defining acceptable roles within a society. These can both constrain and enable entrepreneurship and self-employment by influencing whether they are perceived as desirable and feasible. The chapter illustrates the impact of institutions on entrepreneurship and self-employment by disadvantaged and under-represented groups and offers policy recommendations.