OECD Series on Testing and Assessment

English
ISSN: 
2077-7876 (online)
http://dx.doi.org/10.1787/20777876
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This Series includes publications related to testing and assessment of chemicals; some of them support the development of OECD Test Guidelines (e.g. validation reports, guidance documents, detailed review papers).

 
The Adverse Outcome Pathway for Skin Sensitisation Initiated by Covalent Binding to Proteins

The Adverse Outcome Pathway for Skin Sensitisation Initiated by Covalent Binding to Proteins You or your institution have access to this content

English
Click to Access: 
    http://oecd.metastore.ingenta.com/content/9714341e.pdf
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Author(s):
OECD
03 Sep 2014
Pages:
105
ISBN:
9789264221444 (PDF)
http://dx.doi.org/10.1787/9789264221444-en

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This document describes the state of knowledge of the adverse outcome pathway (AOP) for skin sensitisation initiated by covalent binding to proteins, assesses the weight-of-evidence supporting the AOP, identifies the key events, and identifies databases containing test results related to those key events. AOPs can be incorporated into chemical categories-based assessments or integrated approaches for testing and assessment.
 

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