OECD Guidelines for the Testing of Chemicals, Section 1
- 2074-5753 (online)
The OECD Guidelines for the Testing of Chemicals is a collection of about 150 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of chemicals. They are a set of tools for professionals, used primarily in regulatory safety testing and subsequent chemical and chemical product notification, chemical registration and in chemical evaluation. They can also be used for the selection and ranking of candidate chemicals during the development of new chemicals and products and in toxicology research. This group of tests covers physical-chemical properties.
Test No. 103: Boiling Point
- 27 July 1995
- 9789264069541 (PDF)
This Test Guideline describes methods to determine the boiling point of test substances. The boiling point of a liquid is defined as the temperature (in K) at which the vapour pressure equals the standard atmospheric pressure 101.325 kPa.The influence of impurities on the boiling point depends greatly upon the nature of the impurity. The methods described in this Test Guideline can be applied to liquid and low-melting substances, provided that they do not undergo chemical change below the boiling point. The methods are: the ebulliometer, the dynamic method, the distillation method, the method according to Siwoloboff, the photocell detection, the differential thermal analysis, the differential scanning calorimetry. The photocell detection and thermal analysis permit the determination of boiling as well as melting temperatures. The dynamic method has the advantage that it can also be applied to the determination of the vapour pressure.