OECD Guidelines for the Testing of Chemicals, Section 1

Physical-Chemical properties

Test No. 122: Determination of pH, Acidity and Alkalinity
ISSN :
2074-5753 (online)
DOI :
10.1787/20745753
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The OECD Guidelines for the Testing of Chemicals is a collection of about 150 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of chemicals. They are a set of tools for professionals, used primarily in regulatory safety testing and subsequent chemical and chemical product notification, chemical registration and in chemical evaluation. They can also be used for the selection and ranking of candidate chemicals during the development of new chemicals and products and in toxicology research. This group of tests covers physical-chemical properties.

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Mark Number Date TitleClick to Access
    26 July 2013 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9713151e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-122-determination-of-ph-acidity-and-alkalinity_9789264203686-en
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Test No. 122: Determination of pH, Acidity and Alkalinity
OECD
This Test Guideline describes the procedure for the electronic determination of pH of an undiluted aqueous solution or dispersion, the pH of a dilution of a solution or dispersion in water, or the pH of a chemical diluted to end-use concentration ...
    02 Oct 2012 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9712151e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-109-density-of-liquids-and-solids_9789264123298-en
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Test No. 109: Density of Liquids and Solids
OECD
This Test Guideline lists methods for determining the density of liquids and solids, giving only a succinct description of them. The density of a substance is the quotient of its mass and its volume and is expressed in SI units as kg/m3 at a ...
    02 Oct 2012 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9712161e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-114-viscosity-of-liquids_9789264185180-en
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Test No. 114: Viscosity of Liquids
OECD
This Test Guideline describes methods to measure the viscosity of liquids. Most of the methods listed are appropriate for the investigation of Newtonian liquids. The measurement of non-Newtonian liquids is possible with the rotational viscometer ...
    11 Sep 2006 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9710001e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/summary-of-considerations-in-the-report-from-the-oecd-expert-group-on-physical-chemistry_9789264013391-en
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Summary of Considerations in the Report from the OECD Expert Group on Physical Chemistry
OECD
    11 July 2006 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9712301e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-123-partition-coefficient-1-octanol-water-slow-stirring-method_9789264015845-en
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Test No. 123: Partition Coefficient (1-Octanol/Water): Slow-Stirring Method
OECD
This Test Guideline describes the slow-stirring method, which permits the determination of the 1-octanol/water partition coefficient (POW) values up to a log POW of 8.2. The partition coefficient between water and 1-octanol (POW) is defined as the ...
    11 July 2006 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9710401e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-104-vapour-pressure_9789264069565-en
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Test No. 104: Vapour Pressure
OECD
This Test Guideline describes eight methods to measure the vapour pressure. Each one can be applied in different vapour pressure ranges. The vapour pressure (in Pascal) of a substance is defined as the saturation pressure above a solid or liquid ...
    23 Nov 2004 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9711101e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-111-hydrolysis-as-a-function-of-ph_9789264069701-en
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Test No. 111: Hydrolysis as a Function of pH
OECD
This Test Guideline describes a laboratory test method to assess abiotic hydrolytic transformations of chemicals in aquatic systems at pH values normally found in the environment (pH 4 – 9). This Guideline is designed as a tiered approach; each tier ...
    23 Nov 2004 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9711701e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-117-partition-coefficient-n-octanol-water-hplc-method_9789264069824-en
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Test No. 117: Partition Coefficient (n-octanol/water), HPLC Method
OECD
This Test Guideline describes the HPLC method, which permits to determine the partition coefficient (n-octanol/water) (Pow). Reverse phase HPLC is performed on analytical columns packed with a solid phase containing long hydrocarbon chains ...
    22 Jan 2001 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9712101e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-121-estimation-of-the-adsorption-coefficient-koc-on-soil-and-on-sewage-sludge-using-high-performance-liquid-chromatography-hplc_9789264069909-en
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Test No. 121: Estimation of the Adsorption Coefficient (Koc ) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC)
OECD
This Test Guideline describes an experimental method using HPLC for the estimation of the adsorption coefficient Koc in soil and in sewage sludge. The adsorption coefficient is defined as the ratio between the concentration of the substance in the ...
    21 Jan 2000 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9710601e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-106-adsorption-desorption-using-a-batch-equilibrium-method_9789264069602-en
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Test No. 106: Adsorption -- Desorption Using a Batch Equilibrium Method
OECD
This Test Guideline is aimed at estimating the adsorption/desorption behaviour of a chemical on different soil types. The goal is to obtain a sorption value which can be used to predict partitioning under a variety of environmental conditions; to ...
    21 Jan 2000 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9712001e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-120-solution-extraction-behaviour-of-polymers-in-water_9789264069886-en
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Test No. 120: Solution/Extraction Behaviour of Polymers in Water
OECD
This Test Guideline describes a method to analyse the solution/extraction behaviour of polymers in water, which uses the flask method with modifications. Three samples of 10 g of particles of the test substance are weighed into each of three vessels ...
    14 June 1996 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9711801e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-118-determination-of-the-number-average-molecular-weight-and-the-molecular-weight-distribution-of-polymers-using-gel-permeation-chromatography_9789264069848-en
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Test No. 118: Determination of the Number-Average Molecular Weight and the Molecular Weight Distribution of Polymers using Gel Permeation Chromatography
OECD
This Test guideline describes the Gel Permeation Chromatography (GPC). This method permits to determine the molecular weight distribution and the average molecular weights (Mn, Mw). GPC is a special type of liquid chromatography in which the sample ...
    14 June 1996 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9711901e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-119-determination-of-the-low-molecular-weight-content-of-a-polymer-using-gel-permeation-chromatography_9789264069862-en
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Test No. 119: Determination of the Low Molecular Weight Content of a Polymer Using Gel Permeation Chromatography
OECD
This Test guideline describes the Gel Permeation Chromatography (GPC). This method permits to determine the molecular weight distribution and the average molecular weights (Mn, Mw). GPC is a special type of liquid chromatography in which the sample ...
    27 July 1995 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9710201e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-102-melting-point-melting-range_9789264069527-en
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Test No. 102: Melting Point/ Melting Range
OECD
This Test Guidelines describes several methods and devices to determine the temperature or temperature range of the phase transition from the solid to the liquid state or from the liquid to the solid state. The melting point is defined as the ...
    27 July 1995 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9710301e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-103-boiling-point_9789264069541-en
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Test No. 103: Boiling Point
OECD
This Test Guideline describes methods to determine the boiling point of test substances. The boiling point of a liquid is defined as the temperature (in K) at which the vapour pressure equals the standard atmospheric pressure 101.325 kPa. The ...
    27 July 1995 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9710501e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-105-water-solubility_9789264069589-en
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Test No. 105: Water Solubility
OECD
This Test Guideline describes methods to determine the water solubility of test substances. The water solubility of a substance is the saturation mass concentration of the substance in water at a given temperature. This guideline addresses the ...
    27 July 1995 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9710701e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-107-partition-coefficient-n-octanol-water-shake-flask-method_9789264069626-en
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Test No. 107: Partition Coefficient (n-octanol/water): Shake Flask Method
OECD
This Test Guideline describes a method to determine experimentally Pow values in the range log Pow between -2 and 4 (occasionally up to 5). This method can not be used with surface-active materials. The partition coefficient is defined as the ratio ...
    27 July 1995 Test No. 109: Density of Liquids and Solids
OECD
This Test Guideline lists methods for determining the density of liquids and solids, giving only a very succinct description of them. The density of a substance is the quotient of its mass and its volume and is expressed in kg/m3. Several methods ...
    27 July 1995 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9711501e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-115-surface-tension-of-aqueous-solutions_9789264069787-en
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Test No. 115: Surface Tension of Aqueous Solutions
OECD
This Test Guideline describes methods to determine the surface tension (in N/m) of aqueous solutions. The methods are based on the measurement of the force which it is necessary to exert vertically on a stirrup or ring, in contact with the surface ...
    12 May 1981 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9710101e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-101-uv-vis-absorption-spectra_9789264069503-en
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Test No. 101: UV-VIS Absorption Spectra
OECD
This Test Guideline describes the determining of the ultraviolet-visible (UV-VIS) absorption spectrum of a chemical compound to have some indication of the wavelengths at which the compounds may be susceptible to photochemical degradation ...
    12 May 1981 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9710801e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-108-complex-formation-ability-in-water_9789264069640-en
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Test No. 108: Complex Formation Ability in Water
OECD
This Test Guideline describes the polarographic method. The ability of a substance to form complexes with metals can be assessed by means of polarographic techniques which allow the determination of stability constants for some complexes. The ...
    12 May 1981 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9711001e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-110-particle-size-distribution-fibre-length-and-diameter-distributions_9789264069688-en
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Test No. 110: Particle Size Distribution/ Fibre Length and Diameter Distributions
OECD
This Test Guideline describes two methods. These tests are applicable only to water insoluble (solubility
    12 May 1981 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9711201e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-112-dissociation-constants-in-water_9789264069725-en
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Test No. 112: Dissociation Constants in Water
OECD
This Test Guideline describes the methods allowing the determination of the dissociation constants in water. The dissociation is the reversible splitting into two or more chemical species which may be ionic. The determination of the dissociation ...
    12 May 1981 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9711301e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-113-screening-test-for-thermal-stability-and-stability-in-air_9789264069749-en
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Test No. 113: Screening Test for Thermal Stability and Stability in Air
OECD
This Test Guideline describes methods for determining storage stability of a substance with respect to heat and air. Two methods are applicable to homogeneous solid and liquid substances and to mixtures of these: the accelerated storage test and the ...
    12 May 1981 Test No. 114: Viscosity of Liquids
OECD
This Test Guideline describes methods to measure the viscosity of liquids. The methods listed are appropriate in principle for the investigation of Newtonian liquids. The measurement of non-Newtonian liquids is only possible with the rotational ...
    12 May 1981 Click to Access: 
    http://oecd.metastore.ingenta.com/content/9711601e.pdf
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  • http://www.keepeek.com/Digital-Asset-Management/oecd/environment/test-no-116-fat-solubility-of-solid-and-liquid-substances_9789264069800-en
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Test No. 116: Fat Solubility of Solid and Liquid Substances
OECD
This Test Guideline describes a method to determine the fat solubility of solid and liquid substances. The fat solubility of a substance is one of the data for evaluating the storage of lipid soluble materials in biological tissue. This test method ...
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