OECD Series on Testing and Assessment

ISSN :
2077-7876 (online)
DOI :
10.1787/20777876
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This is a selection of the Series on Testing and Assessment which are the working papers related to the development of the OECD Guidelines for Testing of Chemicals. The Series also contains guidance documents on the assessment of the hazards of chemicals including (Quantitive) Structure-Activity Relationships.

 
Guidance Document on the Recognition, Assessment and Use of Clinical Signs as Human Endpoints for Experimental Animals Used in Safety Evaluation

Guidance Document on the Recognition, Assessment and Use of Clinical Signs as Human Endpoints for Experimental Animals Used in Safety Evaluation You or your institution have access to this content

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Author(s):
OECD
Publication Date :
10 May 2002
Pages :
39
ISBN :
9789264078376 (PDF)
DOI :
10.1787/9789264078376-en

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The purpose of this Guidance Document is to apply the principles of the Three Rs to the use of animals in regulatory toxicity tests. The OECD encourages the humane use of animals in regulatory toxicity and safety evaluation studies and fully endorses the principles of the 3Rs, Replacement, Reduction, Refinement.